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TeachMeFinance.com - explain Lowest Observed Adverse Effect Level (LOAEL) Lowest Observed Adverse Effect Level (LOAEL) The lowest level of a stressor that causes statistically and biologically significant differences in test samples as compared to other samples subjected to no stressor. About the author Mark McCracken Author: Mark McCracken is a corporate trainer and author living in Higashi Osaka, Japan. He is the author of thousands of online articles as well as the Business English textbook, "25 Business Skills in English". Copyright © 2005 by Mark McCracken, All Rights Reserved. TeachMeFinance.com is an informational website, and should not be used as a substitute for professional medical, legal or financial advice. Information presented at TeachMeFinance.com is provided on an "AS-IS" basis. Please read the disclaimer for details.