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TeachMeFinance.com - explain Lipid Solubility Lipid Solubility The maximum concentration of a chemical that will dissolve in fatty substances. Lipid soluble substances are insoluble in water. They will very selectively disperse through the environment via uptake in living tissue. About the author Mark McCracken Author: Mark McCracken is a corporate trainer and author living in Higashi Osaka, Japan. He is the author of thousands of online articles as well as the Business English textbook, "25 Business Skills in English". Copyright © 2005 by Mark McCracken, All Rights Reserved. TeachMeFinance.com is an informational website, and should not be used as a substitute for professional medical, legal or financial advice. Information presented at TeachMeFinance.com is provided on an "AS-IS" basis. Please read the disclaimer for details.